Robotic Lab Assistant

PUBLICATIONS

Eric Koehn's Published Research

  1. Eric M. Koehn, John A. Latham, Tara Armand, Robert L. Evans, Xiongying Tu, Carrie M. Wilmot, Anthony T. Iavarone, and Judith P. Klinman, Discovery of hydroxylase activity for PqqB provides a missing link in the pyrroloquinoline quinone biosynthetic pathway, J. Am. Chem. Soc. 2019,141, 10, 4398-4405

  2. Diybendu Mondal, Eric M. Koehn, Jianjun Yao, David F. Wiemer and Amnon Kohen, Chemo-enzymatic synthesis of the exocyclic olefin isomer of thymidine monophosphate, Bioorg Med Chem. 2018, 26(9), 2365-2371

  3. Eric M. Koehn, Laura L. Perissinotti, Salah Moghram, Arjun Prabhakar, Scott A. Lesley, Irimpan I. Mathews, and Amnon Kohen, The folate binding site of flavin-dependent thymidylate synthase, Proc. Natl. Acad. Sci. 2012, 109, 39, 15722-15727 

  4. Tatiana Mishanina*, Eric M. Koehn*, John A. Conrad, Bruce A. Palfey, Scott A. Lesley, and Amnon Kohen, Trapping of an Intermediate in the Reaction Catalyzed by Flavin-Dependent Thymidylate Synthase. J. Am. Chem. Soc. 2012, 134, 4442-4448. * Equal contribution

  5. Tatiana Mishanina, Eric M. Koehn and Amnon Kohen, Mechanisms and inhibition of uracil methylating enzymes. Bioorg. Chem. 2012, 43, 37-43 

  6. Eric M. Koehn and Amnon Kohen, Flavin-dependent thymidylate synthase: A novel pathway towards thymine. Arch. Biochem. Biophys. 2010, 496, 96-102

  7. Eric M. Koehn, Todd Fleischmann, John A. Conrad, Bruce Palfey, Scott A. Lesley, Irimpan I. Mathews and Amnon Kohen, An unusual mechanism of thymidylate biosynthesis in organisms containing the thyX gene. Nature 2009, 458, 919-923

  8. Zhen Wang, Anatoly Chernyshev, Eric M. Koehn, Tony D. Manuel, Scott A. Lesley, and Amnon Kohen, Oxidase Activity of a Flavin-Dependent Thymidylate Synthase. FEBS J. 2009, 276 (10), 2801-2810 

  9. Anatoly Cherneychev, Todd Fleischmann, Eric M. Koehn, Scott A. Lesley, and Amnon Kohen, The relationships between oxidase and synthase activities of flavin dependent thymidylate synthase (FDTS). Chem. Commun. 2007, 2861-2863